Estriol Resources

Women’s International Pharmacy is dedicated to the education of our customers and practitioners on bioidentical hormone therapies. This page highlights various educational resources and abstracts that explore the use of estriol, one of the body’s natural forms of estrogen.

Vaginal Use of Estriol

Estriol is one of the three main estrogens made in a woman’s body. Discover how the use of vaginal estriol can improve the condition of the urinary tract and vaginal tissue.

Estriol: Safety and Efficacy

Dr. Kathleen A. Head explores the safety and efficacy of estriol and its effect on controlling symptoms of menopause, such as hot flashes, insomnia, vaginal dryness, and frequent urinary tract infections.

Bioidentical Hormone Review

Dr. Deborah Moskowitz reviews the safety and efficacy of bioidentical hormones for the management of menopause and related health risks. Discover how estriol is used in bioidentical hormone therapy.

The Bioidentical Hormone Debate

Dr. Kent Holtorf evaluates evidence comparing bioidentical hormones, including progesterone, estradiol, and estriol, with the commonly used non-bioidentical versions of HRT for risks for breast cancer and cardiovascular disease, physiologic actions on breast tissue, and clinical efficacy.

Intravaginal Estriol Cream

Dr. Raul Raz and Dr. Walter E Stamm research Intravaginal Estriol in Postmenopausal Women with Recurrent Urinary Tract Infections.

Abstract: Comparison of long-term effects of oral estriol with the effects of conjugated estrogen

This abstract discusses the investigation of the long-term effects of oral estriol on bone mineral density and bone turnover in early menopausal women.

Abstract: Estriol, conjugated equine estrogens, and alendronate therapy for osteoporosis

This abstract illustrates a study that evaluated the efficacy of various medications, included estriol, prescribed to women for osteoporosis between 1992 and 2005 at the Menopause Clinic of Tokyo Medical and Dental University Hospital, Japan.

Abstract: Treatment of Multiple Sclerosis with the Pregnancy Hormone Estriol

This abstract explores a study that utilized pregnancy doses of estriol for the treatment of multiple sclerosis.

Abstract: Transvaginal estriol administration in postmenopausal women: a double blind comparative study of two different doses.

This abstract describes a study that treated a group of 72 postmenopausal women for 4 weeks with vaginal suppositories containing 0.1 or 1 mg of estriol. Each dose achieved improvement of urogenital symptoms.

Abstract: Estriol: emerging clinical benefits

This abstract reviews literature from 1974 to 2016 with estriol in the title with emphasis on publications including nonpregnant females. The conclusion from these articles is that estriol offers benefits for postmenopausal women with reduced risks that are normally associated with traditional hormone therapies.

Estriol: The “Good” Estrogen – Advances and Updates in its Clinical Uses

This review article updates on the clinical effects and benefits of estriol. Additionally, it explores the documented advances that support the benefits of estriol treatment for autoimmune conditions.

Autoimmune Disease: When our immune system goes haywire

This article features estriol in its treatment of multiple sclerosis. The effects of oral hormonal treatment for MS, tested by Dr. Nancy Sicotte and colleagues, showed that estriol, a pregnancy hormone, when given to nonpregnant women with MS, helped to decrease MS symptoms.

Skin Deep Look at Hormones

This article explores the effects of hormones on skin. Specific to estriol, a study using topical estriol 0.3% cream showed improved elasticity and firmness of the skin and decreased wrinkle depth and pore sizes.

A Quiet Epidemic of Bladder Troubles

This piece discusses bladder health and urinary incontinence. Through exploring hormone therapies to treat urinary issues, estriol is discussed for treating chronic urinary tract infections.

More Resources

Explore additional resources on hormones, bioidentical hormone replacement therapy, and more.