Oral Progesterone Improves Hot Flashes and Night Sweats

Written by Kathy Lynch, PharmD – Women’s International Pharmacy


A recent study supports the common belief that oral progesterone helps with post-menopausal symptoms such as hot flashes and night sweats. The study included 133 healthy women, ages 44 to 62, who received either 300 mg oral progesterone or a placebo for a twelve-week trial period.

The women who took progesterone described significant decreases in the frequency and severity of both day and night-time vasomotor symptoms. In addition, they reported significant improvement in their sleep quality.

  • Hitchcock CL, Prior JC. Oral micronized progesterone for vasomotor symptoms-a placebo-controlled randomized trial in healthy postmenopausal women.
    2012 Aug;19(8):886-93. doi: 10.1097/gme.0b013e318247f07a.